Mylisa (Pilione) Parette
Was a Postdoctoral Researcher in CIDD until 2006
Current email: mparette@keystonenano.com
Research
I studied host-pathogen interactions using a gram-negative respiratory pathogen, Bordetella bronchiseptica.
B. bronchiseptica can infect a wide range of mammals and contributes to the pathology of atrophic rhinitis in pigs, kennel cough in dogs and snuffles in rabbits.
My research has ranged from molecular studies of receptor interactions during infection to population level studies characterizing the evolution of antigen-encoding genes.
Study systems
Bordetella host-pathogen interactions
Publications
Pilione MR, Agosto LM, Kennett MJ & Harvill ET (2006) CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection. Cellular Microbiology 8: 758-768
Pilione MR & Harvill ET (2006) The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance. Infect. Immun. 74: 1043-1049
Kirimanjeswara GS, Mann PB, Pilione MR, Kennett MJ & Harvill ET (2005) The complex mechanism of antibody-mediated clearance of Bordetella from the lungs requires TLR4. J Immunol. 175:7504-7511
Pilione MR, Pishko EJ, Preston A, Maskell DJ & Harvill ET (2004) pagP is required for resistance to antibody-mediated complement lysis during Bordetella bronchiseptica respiratory infection. Infect. Immun. 72:2837-2842
Pishko EJ, Kirimanjeswara GS, Pilione MR, Gopinathan L, Kennett MJ & Harvill ET (2004) Antibody-mediated bacterial clearance from the lower respiratory tract of mice requires complement component C3. Eur. J Immunol. 34:184-193
people