Isabella M Cattadori
Study systems include
Hernandez A., Poole A., Cattadori I.M. (2012). Climate changes influence free-living stages of soil-transmitted parasites of European rabbits. Global Change Biology, DOI: 10.1111/gcb.12106.
Takar J., Pathak A.K., Murphy L., Albert R., Cattadori I.M. (2012) Network model of immune responses reveals key effectors to single and coinfection kinetics by a respiratory bacterium and a gastrointestinal helminth. PLoS Computational Biology, 8: e1002345.
Kerr P.J., Ghedin E., DePasse J.V., Fitch A., Cattadori I.M., Hudson P.J., Tscharke D.C., Read A.F., Holmes E.C. 2012 Evolutionary History and Attenuation of Myxoma virus on Two Continents. PLoS Pathogens 8(10): e1002950.
Murphy L., Nalpas N., Stear M., Cattadori I.M. (2011). Explaining patterns of infection in free living populations using laboratory immune experiments. Paras. Immunol., 33: 287-302.
Pathak A. K., Creppage K., Werner J., Cattadori I.M. (2010). Immune regulation of a chronic bacteria infection and consequences for pathogen transmission: the case of Bordetella bronchiseptica in rabbits. BMC microbiology, 10: 226. doi:10.1186/1471-2180-10-226.
I am interested in the mechanisms of host-parasite interaction, how hosts modulate concurrent infections, how infecting agents adapt their traits to optimize fitness and long term persistence at host population level and how host heterogeneities affect these interactions. Some of the questions I am addressing are: How is the dynamics of an infecting agent altered by a second infecting species? How does immunity affect shedding of infecting particles? Do close related hosts exhibit similar susceptibility to infections?
I am also interested in understanding how environmental conditions affect risk of infection. Questions I am addressing are: How do climate changes affect dynamics of parasite free living stages? How do habitat and host spatial structure influence the force of infection?
My current work focuses on:
- Immuno-epidemiology of host-parasite interactions
- Concurrent infections
- Host heterogeneities and consequences for parasite dynamics
- Climate change and risk of infection