Isabella M Cattadori
Study systems include
Kerr, P., Liu, J., Cattadori, I.M., Ghedin E., Read, A.F., Holmes, E. 2015. Myxoma virus and the leporipoxviruses: an evolutionary paradigm. Viruses, 7:1020-1061. pdf
Lambert, K.A., Pathak, A.K., Cattadori, I.M. 2015. Does host immunity influence helminth egg hatchability in the environment? Journal of Helmonthology, 89(04):446-452.
Cattadori I.M., Boag B., Wagner B.R., Wodzinski L.A., Boag B. 2014. Infections do not predict shedding in co-infections with two helminths from a natural system. Ecology, 95(6):1684-92. pdf
Kerr, P., Rogers, M.B,. Fitch, A., DePasse, J., Cattadori, I.M., Twaddle, A.C., Hudson, P.J., Tscharke, D.C., Read, A.F., Holmes, E., Ghedin, E. 2013. Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread. Journal of Virology. 87(23):12900. pdf
Kerr, P., Rogers, M.B,. Fitch, A., DePasse, J., Cattadori, I.M., Hudson, P.J., Tscharke, D.C., Holmes, E., Ghedin, E. 2013. Comparative analysis of the complete genome sequence of the California MSW strain of myxoma virus reveals potential host adaptations. Journal of Virology. 87(22):12080. pdf
Boag, B., Hernandez, A.D., Cattadori, I.M. 2013. Observations on the epidemiology and interactions between myxomatosis, occidiosis and helminth parasites in a wild rabbit population in Scotland. pdf
Murphy L., Pathak A.K. & Cattadori I.M. 2013. A co-infection with two gastrointestinal nematodes alters host immune responses and only partially parasite dynamics. Parasite Immunology, 35: 421-432. pdf
Hernandez A., Poole A., Cattadori I.M. 2013. Climate changes influence free-living stages of soil-transmitted parasites of European rabbits. Global Change Biology, 19: 1028-1042. pdf
Pathak A.K., Pelensky C., Boag B., Cattadori I.M. 2012. Immuno-epidemiology of chronic bacteria-helminth co-infection: observations from the field and evidence from the laboratoy. International Journal for Parasitology, 42: 647-655. pdf
Thakar J., Pathak A.K., Murphy L., Albert R., Cattadori I.M. 2012. Network model of immune responses reveals key effectors to single and coinfection kinetics by a respiratory bacterium and a gastrointestinal helminth. PLoS Computational Biology, 8: e1002345. pdf
Kerr P.J., Ghedin E., DePasse J.V., Fitch A., Cattadori I.M., Hudson P.J., Tscharke D.C., Read A.F., Holmes E.C. 2012 Evolutionary History and Attenuation of Myxoma virus on Two Continents. PLoS Pathogens, 8(10): e1002950. pdf
Pathak A. K., Creppage K., Werner J., Cattadori I.M. 2010. Immune regulation of a chronic bacteria infection and consequences for pathogen transmission: the case of Bordetella bronchiseptica in rabbits. BMC microbiology, 10: 226. doi:10.1186/1471-2180-10-226. pdf
I am interested in the mechanisms of host-parasite interaction, how hosts modulate concurrent infections, how infecting agents adapt their traits to optimize fitness and long term persistence in the host population and how host heterogeneities affect these interactions. Some of the questions I address are: How is the dynamics of an infecting agent altered by a second infecting species? How does immunity affect parasite/pathogen shedding? Do close related hosts exhibit similar susceptibility to infections?
I am also interested in understanding how environmental conditions affect risk of infection. Questions I ask are: How do climate changes affect dynamics of parasite free living stages? Do climate changes equally affect immune and less-immune regulated parasite species? How do habitat and host spatial structure influence the force of infection?
My current working topics are :
- Immuno-epidemiology of host-parasite interactions
- Concurrent infections
- Host heterogeneities and consequences for parasite dynamics
- Climate change and risk of infection