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Mary Kennett

Study systems include

Bordetella
Bacillus anthracis (Sterne strain)

Selected publications

Loving CL, Kennett M, Lee GM, Grippe VK, Merkel TJ (2007) Murine aerosol challenge model of anthrax. Infect Immun. 75: 2689-98

Mann P, Goebel E, Barbarich J, Pilione MR, Kennett M, Harvill ET (2007) Use of a genetically defined double mutant strain of Bordetella bronchiseptica lacking adenylate cyclase and type III secretion as a live vaccine. Infect Immun. 75: 3665-72.

Pilione MR, Agosto LM, Kennett MJ & Harvill ET (2006) CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection. Cellular Microbiology 8: 758-768

Kirimanjeswara GS, Agosto LM, Kennett MJ, Bjornstad ON & Harvill ET (2005). Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis. J. Clin. Invest. 115: 3594-3601

Mary Kennett

Director, Animal Resource Program;
Professor, Department of Veterinary & Biomedical Sciences

Email: mjk26@psu.edu

Phone: 814-865-1495

Office: 101 Centralized Biological Laboratory

Research interests

My primary research interest is the pathogenesis of infectious disease, in particular, identification and characterization of virulence factors involved in:

  • Initial colonization of the host
  • Mucosal immune responses

This research currently focuses on Bordetella bronchiseptica, B. pertussis and B. parapertussis infections in transgenic and immunocompromised mice. We are investigating the pathogenesis of respiratory infections and the specific immune responses involved in clearing bacteria from the upper and lower respiratory tract.

My other interests include laboratory animal resource management, comparative medicine, animal behavior and well being, and the preventative and clinical veterinary care of research animals.

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