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Stephan Schuster

Study systems include

Helicobacteraceae (e.g. Helicobacter pylori, H. hepaticus)

Campylobacteraceae (e.g. Campylobacter jejuni, Wolinella succinogenes)

Bdellovibrio bacteriovorus, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria

Selected publications

Huson DH, Auch AF, Qi J & Schuster SC (2007). MEGAN analysis of metagenomic data. Genome Res. 17: 377-386

Velicer GJ, Raddatz G, Keller H, Deiss S, Lanz C, Dinkelacker I & Schuster SC (2006). Comprehensive mutation identification in an evolved bacterial cooperator and its cheating ancestor. PNAS 103: 8107-8112

Poinar HN, Schwarz C, Qi J, Shapir B, MacPhee RDE, Buigues B, Alexei Tikhonov A, Huson DH, Tomsho LP, Auch A, Rampp M, Miller W & Schuster SC (2005). Metagenomics to Paleogenomics: Large-Scale Sequencing of Mammoth DNA. Science.

Schuster SC & Gottschalk, G (2005). Microbial genetics in its second decade. Curr. Opinion Microbiol. 8: 495-6

Rendulic S, Jagtap P, Rosinus A, Eppinger M, Baar C, Lanz C, Keller H, Lambert C, Evans KJ, Goesmann A, Meyer F, Sockett RE & Schuster SC (2004). A predator unmasked: Life cycle of Bdellovibrio bacteriovorus from a genomic perspective. Science 303: 689-692

Stephan Schuster

Professor of Biochemistry and Molecular Biology

Email: scs@bx.psu.edu

Phone: 814-863-9278

Office: 310 Wartik Laboratory

Research interests

Our group studies the genomes from related bacteria: host-adapted and free-living species. We are interested in the molecular mechanisms that have driven the speciation process from free-living last common ancestors to the obligatory pathogenic species that we see today.

  • We analyze the complete genome sequence of microbial species
  • We then conduct a detailed bioinformatic analysis
  • A functional analysis then tests experimentally the predicted gene function

 

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