Center for Infectious Disease Dynamics
CIDD brings together scientists in a range of complementary disciplines to innovate in infectious disease research.
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- Job opportunities
- Postdoctoral fellowship in molecular virology and immunology Postdoctoral research fellowship opening to participate in an integrated project on the temporal and spatial dynamics of cellular innate responses to viral infection and coinfection. — Posted Jul 03, 2009
- Faculty Appointments in Infectious Disease: The Evolution & Dynamics of Pathogens We are seeking interactive, interdisciplinary candidates who are Mathematicians, Physicists, Statisticians, Climate Modelers or Biologists, to work across disciplines and identify novel insights and solutions to managing the disease burden. — Posted Jul 02, 2009
- Highlights from recent research
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Targeted insecticides could reduce malaria
Using insecticides indiscriminately can cause mosquitoes to built up a resistance to the insecticides creating a never ending race to engineer new insecticides. By changing the approach and creating insecticides that only target older mosquitoes the pressure to reproduce is reduced and the chances of building a resistance are greatly reduced.
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- Read paper on journal website : How to make evolution-proof insecticides for Malaria control, PLoS Biology (2009)
- Go to a press release about this research
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Climate change and fungal disease in amphibians
Many amphibian extinctions in recent decades were apparently caused by a fungal disease. But what underlies increased disease incidence? Has climate change made it easier for the fungus to spread? Or has the fungus been introduced in more places independently of climate change? A new data analysis shows that neither theory explains observed amphibian population declines well. Instead, a mix of factors may be responsible
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- Read paper on journal website : Evaluating the links between climate, disease spread, and amphibian declines, PNAS (2008)
- Go to a press release about this research
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Tropical reservoir for human influenza?
An analysis of more than 1300 complete influenza genomes shows different evolutionary patterns for two important viral subtypes (A/H1N1 and A/H3N2). Changes in diversity through time in northern and southern hemispheres suggest that for each of these subtypes, new strains arise from a reservoir in the tropics and move out to temperate regions.
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- Read paper on journal website : The genomic and epidemiological dynamics of human influenza A virus, Nature (2008)
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Influenza A virus: history of reassortment
Genetic sequences collected between 1918 and 2005 indicate that reassortment happens frequently in the evolutionary history of the Influenza A virus, including in the emergence of epidemic viruses.
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- Read paper on journal website : Multiple Reassortment Events in the Evolutionary History of H1N1 Influenza A Virus Since 1918, PLoS Pathogens (2008)
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Predicting the unpredictable: measles outbreaks in sub-Saharan Africa
Strong seasonal variations in transmission mean it is difficult to predict the size of measles epidemics in Niger from year to year. The large variability in annual outbreaks has implications for efforts to control outbreaks by vaccination.
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- Read paper on journal website : The dynamics of measles in sub-Saharan Africa, Nature (2008)
- Go to a press release about this research
