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Stephan Schuster
Study systems include
Helicobacteraceae (e.g. Helicobacter pylori, H. hepaticus)
Campylobacteraceae (e.g. Campylobacter jejuni, Wolinella succinogenes)
Bdellovibrio bacteriovorus, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria
Selected publications
Huson DH, Auch AF, Qi J & Schuster SC (2007). MEGAN analysis of metagenomic data. Genome Res. 17: 377-386
Velicer GJ, Raddatz G, Keller H, Deiss S, Lanz C, Dinkelacker I & Schuster SC (2006). Comprehensive mutation identification in an evolved bacterial cooperator and its cheating ancestor. PNAS 103: 8107-8112
Poinar HN, Schwarz C, Qi J, Shapir B, MacPhee RDE, Buigues B, Alexei Tikhonov A, Huson DH, Tomsho LP, Auch A, Rampp M, Miller W & Schuster SC (2005). Metagenomics to Paleogenomics: Large-Scale Sequencing of Mammoth DNA. Science.
Schuster SC & Gottschalk, G (2005). Microbial genetics in its second decade. Curr. Opinion Microbiol. 8: 495-6
Rendulic S, Jagtap P, Rosinus A, Eppinger M, Baar C, Lanz C, Keller H, Lambert C, Evans KJ, Goesmann A, Meyer F, Sockett RE & Schuster SC (2004). A predator unmasked: Life cycle of Bdellovibrio bacteriovorus from a genomic perspective. Science 303: 689-692
Associate Professor of Biochemistry and Molecular Biology
Email: scs@bx.psu.edu
Phone: (814) 863-9278
Office: 310 Wartik Laboratory
Research interests
Our group studies the genomes from related bacteria: host-adapted and free-living species. We are interested in the molecular mechanisms that have driven the speciation process from free-living last common ancestors to the obligatory pathogenic species that we see today.
- We analyze the complete genome sequence of microbial species
- We then conduct a detailed bioinformatic analysis
- A functional analysis then tests experimentally the predicted gene function
